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Stephen Fry as Leonardo da Vinci (voice) |
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Daisy Ridley as Princess Marguerite (voice) |
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Marion Cotillard as Louise de Savoy (voice) |
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Matt Berry as Pope Leo XI (voice) |
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Natalie Palamides as Pierre Nepveu / Antonio de Beatis (voice) |
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Jim Capobianco as Cardinal of Aragon (voice) |
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Ben Stranahan as Page (voice) |
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Jane Osborn as Gravedigger Jane (voice) |
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Gauthier Battoue as Francis I of France (voice) |
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John Gilkey as Gravedigger John / Giuliano (voice) |
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Max Baumgarten as Il Boccador / King Charles of Spain (voice) |
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Daniel Swan as King Henry the VIII (voice) |
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Angelino Sandri as Francesco Melzi (voice) |
| Directing | Pierre-Luc Granjon | Director |
| Production | Kat Alioshin | Executive Producer |
| Production | Jay Burnley | Executive Producer |
| Production | Keanu Mayo | Executive Producer |
| Production | Katherine Waddell | Executive Producer |
| Production | Ryan Clarkson | Executive Producer |
| Production | Aubin Feroussier | Production Manager |
| Production | Habib Paracha | Executive Producer |
| Production | Christophe Felix | Production Manager |
| Production | Phil Viardo | Executive Producer |
| Art | Nate Stanton | Storyboard Artist |
| Production | Joshua A. Bevan | Co-Executive Producer |
| Production | Kyle Stroud | Executive Producer |
| Costume & Make-Up | Clotilde Laude | Costumer |
| Production | Vince McCarthy | Co-Producer |
| Production | Raymond Sandra | Executive Producer |
| Costume & Make-Up | Pauline Valls | Costume Design |
| Art | Sarah Leuver | Storyboard Artist |
| Costume & Make-Up | Krystina Vorobyeva | Costumer |
| Production | Christopher Massimine | Executive Producer |
| Production | Jarnell Stokes | Executive Producer |
| Production | Ben Stranahan | Executive Producer |
| Production | Chelsea Tieu | Executive Producer |
| Production | Ellen Byrne | Co-Producer |
| Production | Rob McGillivray | Executive Producer |
| Art | Morgane Baux | Set Painter |
| Art | Claire Bochet | Set Painter |
| Production | Chris Capobianco | Executive Producer |
| Art | Jamie Baker | Storyboard Artist |
| Art | Nicola Sammarco | Storyboard Artist |
| Camera | Marijke Van Kets | Director of Photography |
| Production | Nicolas Flory | Executive Producer |
| Production | Eric Vonfeldt | Executive Producer |
| Production | J.D. Zacharias | Executive Producer |
| Costume & Make-Up | Lou Bonelli | Costumer |
| Production | Raymond Fino | Executive Producer |
| Production | Neuman Vong | Executive Producer |
| Art | Samuel Ribeyron | Production Design |
| Art | Virginie Dollat | Set Painter |
| Costume & Make-Up | Quentin Zahaf | Costumer |
| Art | Camille Besnard | Set Painter |
| Art | Arna Selznick | Storyboard Artist |
| Art | Tatiana Moniz | Storyboard Artist |
| Sound | Daisy Ridley | Songs |
| Sound | Marion Cotillard | Songs |
| Production | Adrian Politowski | Producer |
| Production | Jim Capobianco | Producer |
| Production | Don Hahn | Executive Producer |
| Production | Robert Rippberger | Producer |
| Visual Effects | Tomm Moore | Animation |
| Writing | Jim Capobianco | Writer |
| Production | Carmella Casinelli | Executive Producer |
| Directing | Jim Capobianco | Director |
| Production | Lorenz Evans | Executive Producer |
| Crew | Roger Goff | Legal Services |
| Sound | Alex Mandel | Music |
| Production | Kat Alioshin | Line Producer |
| Writing | Tatiana Moniz | Story Artist |
| Crew | Peter Sorg | Cinematography |
| Production | David Lyons | Executive Producer |
| Production | Sita Saviolo | Executive Producer |
| Production | Jeremy Walton | Executive Producer |
| Production | Steve Muench | Executive Producer |
| Production | Jacob Michael Silva | Co-Executive Producer |
| Production | Ilan Urroz | Executive Producer |
| Production | Dave Lugo | Executive Producer |
| Production | Chris Ihlenfeldt | Co-Executive Producer |
| Production | William Nix | Executive Producer |
| Production | Wes Hull | Executive Producer |
| Art | James S. Baker | Additional Storyboarding |
| Sound | Mark Willsher | Scoring Mixer |
