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Kamal Haasan as Vishwanathan / Major Wisam Ahmad Kashmiri |
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Rahul Bose as Omar Qureshi |
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Andrea Jeremiah as Ashmita Subramaniam |
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Pooja Kumar as Dr. Nirupama |
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Shekhar Kapur as Colonel Jagannath |
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Jaideep Ahlawat as Salim |
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Samrat Chakrabarti as Deepak Chatterjee |
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Nassar as Nassar |
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Zarina Wahab as Nirupama's Psychiatrist |
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Miles Anderson as Dr. Dawkins |
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Naren Weiss as Osama bin Laden |
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Mukhtar Khan as Farukh |
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James Babson as Tom Black |
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Jude S. Walko as Captain Joe Black |
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Chris Kotcher as Tollbooth Operator |
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Greg Sammis as FBI Agent |
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David Scott Diaz as FBI Agent Dave |
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Rajesh M. Selva as Abu |
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Atul Tiwari as Detective Peter Manivannan |
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Abhirami as Dr. Nirupama (Voice) |
| Writing | Kamal Haasan | Story |
| Writing | Vairamuthu | Lyricist |
| Art | James R. Cunningham | Production Design |
| Writing | Kamal Haasan | Lyricist |
| Sound | Suraj Jagan | Playback Singer |
| Costume & Make-Up | Ralis Kahn | Makeup Department Head |
| Sound | Shankar Mahadevan | Original Music Composer |
| Sound | Loy Mendonsa | Original Music Composer |
| Sound | Shankar Mahadevan | Playback Singer |
| Art | Boontawee 'Tor' Taweepasas | Production Design |
| Crew | T. Ramesh | Stunt Coordinator |
| Sound | Nikhil D'Souza | Playback Singer |
| Crew | Kaecha Kampakdee | Stunt Coordinator |
| Sound | Indrajit 'Tubby' Sharma | Original Music Composer |
| Sound | Kamal Haasan | Playback Singer |
| Sound | Parikshit Sharma | Original Music Composer |
| Sound | Benny Dayal | Playback Singer |
| Sound | Ehsaan Noorani | Original Music Composer |
| Costume & Make-Up | Gage Hubbard | Makeup Artist |
| Crew | Birju Maharaj | Choreographer |
| Visual Effects | Vivek Soni | Visual Effects Coordinator |
| Directing | Kamal Haasan | Director |
| Camera | Sanu John Varghese | Director of Photography |
| Editing | Mahesh Narayanan | Editor |
| Production | Kamal Haasan | Producer |
| Writing | Atul Tiwari | Dialogue |
| Writing | Kamal Haasan | Screenplay |
| Sound | Marc Glassman | Sound Effects Editor |
| Production | S Shanmugam | Executive Producer |
| Costume & Make-Up | Gautami Tadimalla | Costume Design |
| Editing | John Joseph | Assistant Editor |
| Crew | Lee Whittaker | Stunts Coordinator |
| Writing | Kamal Haasan | Dialogue |
| Production | Prasad Vara Potluri | Producer |
| Sound | Marti D. Humphrey | Sound Mixer |
| Production | Chandrahasan | Producer |
| Art | Lalgudi N. Ilayaraja | Art Direction |
| Directing | Rajesh M. Selva | Assistant Director |
| Crew | Praveen Kumar | Second Unit |
| Art | Nancy Terryn | Art Direction |
| Visual Effects | Madhu Sudhanan | VFX Supervisor |
| Directing | C.S. Karthikeyan | Assistant Director |
| Visual Effects | Abhilash Nanda | Visual Effects Supervisor |
