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Luke Goss as Carl 'Luke' Lucas / Frankenstein |
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Lauren Cohan as September Jones |
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Sean Bean as Markus Kane |
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Danny Trejo as Goldberg |
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Ving Rhames as Weyland |
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Tanit Phoenix as Katrina Banks |
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Robin Shou as 14K |
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Joe Vaz as Rocco |
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Frederick Koehler as Lists |
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Sean Higgs as Hillbilly Con |
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Patrick Lyster as Warden Medford Parks |
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Deobia Oparei as Big Bill |
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Hennie Bosman as Xander Grady |
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Warrick Grier as Calin |
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Danny Keogh as Dr. Klein |
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Tanya van Graan as Holly |
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Ryan Kruger as Fat Guard |
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Robyn LeAnn Scott as Big Angry Female Guard |
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Alex Lorre as Driver |
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Stephen Jennings as Defense Attorney |
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Tyrone Keogh as Camerman #2 |
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Trayan Milenov-Troy as Scars |
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Jenna Saras as Stunning Woman |
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Chase Armitage as Apache |
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Michael Solomon as The Sheik |
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Scott Sparrow as Vinnie |
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Ricky Botsis as Terry |
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Michael Dube as Union Blood Member (as Michael T. Dube) |
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Richard Lothian as Rapist Con |
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Inge Beckmann as Nurse |
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Milton Schorr as Prison Bus Guard |
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Leigh Graves as The D.A |
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Stephanie Schildknecht as Weyland's Secretary |
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Lee-Anne Liebenberg as The Sheik’s Navigator Girl |
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Chelsea King as Big Bill's Navigator Girl |
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Karlien Seegers as Apache’s Navigator Girl |
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Dick Ervasti as Commercial voice (uncredited) |
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Quentin Chong as Triad Assassin |
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Adam Lazarre-White as Opening Narrator (voice) |
| Directing | Roel Reiné | Director |
| Production | Paul W. S. Anderson | Producer |
| Production | Jeremy Bolt | Producer |
| Production | Jan Glaser | Casting |
| Costume & Make-Up | Moira Anne Meyer | Costume Design |
| Writing | Paul W. S. Anderson | Characters |
| Writing | Paul W. S. Anderson | Story |
| Camera | John McKay | Director of Photography |
| Costume & Make-Up | Clinton Smith | Contact Lens Technician |
| Costume & Make-Up | Clinton Smith | Prosthetic Designer |
| Costume & Make-Up | Kerry Skelton | Key Makeup Artist |
| Costume & Make-Up | Gerald Sutherland | Special Effects Makeup Artist |
| Costume & Make-Up | Cailin Nicolson | Special Effects Makeup Artist |
| Directing | Gabriel Williams | First Assistant Director |
| Directing | Gene Gualdi | Second Assistant Director |
| Directing | Shamiel Soni | Second Assistant Director |
| Directing | Christo van Schalkwyk | Second Assistant Director |
| Directing | Frederich Fiela Jonck | Third Assistant Director |
| Art | Dénes Molnár | Concept Artist |
| Art | Andor Záhonyi | Concept Artist |
| Art | Cecelia van Straaten | Draughtsman |
| Art | Lucille Doman | Graphic Designer |
| Art | Kate Hilson | Graphic Designer |
| Art | Szentgyörgyi Ottó | Graphic Designer |
| Art | Damian Fermor | Property Master |
| Art | Vicky Sawkins | Set Dresser |
| Art | Jacobus Smit | Set Dresser |
| Art | Mark Risk | Storyboard Artist |
| Production | Ashley Dennis | Casting Assistant |
| Production | Jaci Cheiman | Casting Coordinator |
| Costume & Make-Up | Jacomina Jankowitz | Assistant Costume Designer |
| Costume & Make-Up | Rick de Souza | Key Costumer |
| Art | Marius Pretorius | Painter |
| Art | Lisa Van Der Merwe | Painter |
| Camera | Bernard Esterhuysen | Digital Imaging Technician |
| Camera | Keith Smith | Dolly Grip |
| Lighting | Brandon Daniels | Electrician |
| Lighting | Zolani Gojo | Electrician |
| Lighting | Myron Mance | Electrician |
| Lighting | Phillip Mhlabane | Electrician |
| Lighting | Quintin Pretorius | Electrician |
| Lighting | Brent Sauls | Electrician |
| Camera | Zane Harrison | First Assistant Camera |
| Lighting | Emmanuel Chonco Sithole | Gaffer |
| Camera | Karl Fredrick | Grip |
| Camera | Regan Mitchell | Grip |
| Camera | Lazarus Seoposenwe | Grip |
| Camera | Jason Venter | Grip |
| Camera | Jens Bacher | Key Grip |
| Camera | Keith Saayman | Libra Head Technician |
| Camera | Johan Horjus | Phantom Operator |
| Camera | Margaret Muggleston | Second Assistant Camera |
| Camera | Nigel Tompkins | Second Assistant Camera |
| Camera | Gerhard Geldenhuys | Second Assistant Camera |
| Visual Effects | Attila Csepy | 3D Artist |
| Visual Effects | Norbert Fuchs | 3D Artist |
| Visual Effects | Miklós Polgár | 3D Artist |
| Visual Effects | Andor Záhonyi | Compositing Lead |
| Visual Effects | Nick Hsieh | Compositing Supervisor |
| Crew | Xiaoming Wang | Compositor |
| Crew | Hansu Zhan | Compositor |
| Visual Effects | Heinrich Maas | Digital Compositor |
| Visual Effects | Dénes Molnár | Digital Compositor |
| Visual Effects | Carl Schröter | Digital Compositor |
| Visual Effects | Yevgen Skorobogatko | Digital Compositor |
| Visual Effects | Gyuri Szlamka | Digital Compositor |
| Visual Effects | Johannes Bogenhauser | Digital Compositor |
| Visual Effects | Oliver Heinrich | Digital Compositor |
| Editing | Avital Shalev | Digital Intermediate Producer |
| Visual Effects | Roman Bazyuchenko | VFX Artist |
| Visual Effects | Patricia Feldmann | VFX Artist |
| Visual Effects | Thomas Lehmann | VFX Artist |
| Costume & Make-Up | Lise-Marie Bothma | Prosthetics |
| Crew | Cordell McQueen | Pyrotechnician |
| Crew | Doug Hardy | Special Effects Technician |
| Crew | Tyrell Kemlo | Special Effects Technician |
| Crew | Calen Van Schalkwyk | Special Effects Technician |
| Sound | Travis MacKay | ADR Mixer |
| Sound | Simon McCormick | ADR Recordist |
| Sound | Ryan Collins | Assistant Sound Editor |
| Sound | Callie Thurman | Assistant Sound Editor |
| Sound | Jacques Pienaar | Boom Operator |
| Sound | Sarah Payan | Dialogue Editor |
| Sound | Lara Dale | Foley Artist |
| Sound | Ellen Heuer | Foley Artist |
| Sound | Brian Dunlop | Foley Editor |
| Sound | A. Josh Reinhardt | Foley Mixer |
| Sound | Conrad Kuhne | Production Sound Mixer |
| Sound | Javier Bennassar | Sound Designer |
| Editing | Sue Gates | Colorist |
| Editing | Rita DaSilva | First Assistant Editor |
| Production | Valerie Rose | Assistant Production Coordinator |
| Crew | Gert Uys | Pilot |
| Crew | Olly Steele | Weapons Master |
| Production | Billi Bruins | Production Accountant |
| Production | Demian Hauptle | Production Assistant |
| Production | Jayson Snyman | Production Assistant |
| Production | Megan Truter | Production Assistant |
| Production | Tina Caldeira | Production Coordinator |
| Crew | Helene Turvey | Unit Publicist |
| Crew | Clinton du Preez | Transportation Captain |
| Sound | Paul Di Franco | Music Supervisor |
| Writing | Tony Giglio | Screenplay |
| Visual Effects | Jeremy Ball | Visual Effects Supervisor |
| Editing | Radu Ion | Editor |
| Editing | Herman P. Koerts | Editor |
| Art | Johnny Breedt | Production Design |
| Art | Andrew Orlando | Art Direction |
| Art | Melinda Launspach | Set Decoration |
| Costume & Make-Up | Megan Tanner | Makeup Department Head |
| Art | Patrick O'Connor | Assistant Art Director |
| Sound | Javier Bennassar | Supervising Sound Editor |
| Sound | Sze-Wun Li | Sound Effects Editor |
| Sound | Leslie Shatz | Sound Re-Recording Mixer |
| Sound | Stephen Webster | Sound Re-Recording Mixer |
| Crew | Cordell McQueen | Special Effects Coordinator |
| Visual Effects | Tyler Kehl | Visual Effects Producer |
| Visual Effects | David Van Woert | Visual Effects Producer |
| Visual Effects | Leo Vezzali | Visual Effects Producer |
| Visual Effects | Steven Hodgson | Visual Effects Supervisor |
| Visual Effects | Oleksandr Kucherov | Visual Effects Supervisor |
| Visual Effects | Laszlo Mates | Visual Effects Supervisor |
| Visual Effects | Anton Mitrakhov | Visual Effects Supervisor |
| Crew | Adam Horton | Stunt Coordinator |
| Camera | Damien Walsh | Camera Operator |
| Camera | Sarel Pretorius | Steadicam Operator |
| Camera | David Bloomer | Still Photographer |
| Costume & Make-Up | Susan Barras | Costume Supervisor |
| Crew | Joy Sapieka | Unit Publicist |
| Production | Morten Nielsen | Location Manager |
| Crew | Zandara Kennedy | Stunts |
| Sound | Paul Haslinger | Original Music Composer |
| Production | Roger Corman | Executive Producer |
| Production | Mike Elliott | Producer |
| Production | Greg Holstein | Associate Producer |
| Production | Paula Wagner | Executive Producer |
| Production | Marvin Saven | Associate Producer |
| Production | Alan Shearer | Line Producer |
| Costume & Make-Up | Talia Barak | Makeup Artist |
| Costume & Make-Up | Jilly Greenham | Hairstylist |
| Costume & Make-Up | Simone Stubbs | Makeup Artist |
| Crew | Luke Rhode | Stunts |
| Crew | François Coetzer | Stunts |
| Writing | Robert Thom | Characters |
| Writing | Ib Melchior | Characters |
| Writing | Charles B. Griffith | Characters |
| Writing | Tony Giglio | Story |
| Production | Genevieve Hofmeyr | Co-Producer |
| Production | Ralph Tuebben | Co-Producer |
| Directing | Mike Elliott | Second Unit Director |
| Crew | Dickey Beer | Stunt Coordinator |
| Crew | Chase Armitage | Stunt Double |
| Crew | Trayan Milenov-Troy | Fight Choreographer |
| Crew | Lee-Anne Liebenberg | Stunt Double |
| Crew | Hans Menck | Stunt Double |
| Crew | Oliver Bailey | Stunts |
| Crew | Jared Cohen | Stunts |
| Crew | Malcolm Cochrane | Stunt Driver |
| Crew | Louis Gouws | Stunt Driver |
| Crew | Dan Hirst | Stunts |
| Crew | Boris Martinez | Stunts |
| Crew | Cordell McQueen | Stunt Driver |
| Crew | Voytec Modrezewski | Stunts |
| Crew | Chantal Nell | Stunts |
| Crew | Paul Pieterse | Stunt Driver |
| Crew | Grant Powell | Stunts |
| Crew | Marc Hyland | Stunts |
| Crew | Allen Irwin | Stunt Driver |
| Crew | Bjorn Steinbach | Stunts |
| Crew | Emmylou Rabe | Stunts |
| Crew | Vernon Willemse | Stunts |
| Crew | Nathan Wheatley | Stunts |
| Crew | Fleur van Eeden | Stunts |
| Crew | Craig Gordon Sobotker | Stunt Driver |
| Camera | Hein de Vos | Camera Operator |
| Camera | Sarel Pretorius | "B" Camera Operator |
| Camera | Peter Belcher | Aerial Camera |
| Sound | Murray Anderson | Music Supervisor |
