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Catherine O'Hara as Mrs. Frankenstein / Weird Girl / Gym Teacher (voice) |
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Martin Short as Mr. Frankenstein / Mr. Burgemeister / Nassor (voice) |
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მარტინ ლანდაუ as Mr. Rzykruski (voice) |
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Charlie Tahan as Victor Frankenstein (voice) |
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Atticus Shaffer as Edgar 'E' Gore (voice) |
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ვაინონა რაიდერი as Elsa Van Helsing (voice) |
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Robert Capron as Bob (voice) |
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James Hiroyuki Liao as Toshiaki (voice) |
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Conchata Ferrell as Bob's Mom (voice) |
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Tom Kenny as New Holland Townsfolk (voice) |
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Frank Welker as Sparky (voice) (uncredited) |
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Dee Bradley Baker as Persephone / Shelly / Were-Rat / Colossus / Mr. Whiskers / Driver (voice) (uncredited) |
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Jeff Bennett as Giant Sea Monkeys (voice) (uncredited) |
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Jon Donahue as Additional Voices (voice) |
| Directing | ტიმ ბარტონი | Director |
| Writing | John August | Screenplay |
| Writing | ტიმ ბარტონი | Idea |
| Writing | ტიმ ბარტონი | Characters |
| Production | Don Hahn | Executive Producer |
| Production | ტიმ ბარტონი | Producer |
| Sound | Mark DeSimone | ADR Mixer |
| Sound | Jason Swanscott | Foley Artist |
| Sound | Andie Derrick | Foley Artist |
| Sound | Peter Burgis | Foley Artist |
| Sound | Simon Diggins | ADR Recordist |
| Sound | Chris Navarro | ADR Mixer |
| Sound | Glen Gathard | Foley Mixer |
| Sound | დენი ელფმანი | Original Music Composer |
| Camera | Peter Sorg | Director of Photography |
| Production | Ronna Kress | Casting |
| Editing | Chris Lebenzon | Editor |
| Production | Allison Abbate | Producer |
| Editing | Mark Solomon | Editor |
| Visual Effects | Cesar Diaz Melendez | Animation |
| Visual Effects | Chris Gilligan | Animation |
| Visual Effects | Chuck Duke | Animation |
| Visual Effects | Kristien Vanden Bussche | Animation |
| Visual Effects | Jody Meredith | Animation |
| Writing | Christian De Vita | Storyboard |
| Visual Effects | Danail Kraev | Animation |
| Visual Effects | Matias Liebrecht | Animation |
| Visual Effects | Daniel Alderson | Animation |
| Writing | Jørgen Klubien | Storyboard |
| Visual Effects | Marjolaine Parot | Animation |
| Visual Effects | Kim Keukeleire | Animation |
| Visual Effects | Rachelle Lambden | Animation |
| Visual Effects | Jens Jonathan Gulliksen | Animation |
| Visual Effects | Pete Dodd | Animation |
| Writing | Dean Roberts | Storyboard |
| Visual Effects | Boris Wolf | Animation |
| Visual Effects | Steve Warne | Animation |
| Visual Effects | Mark Waring | Animation Supervisor |
| Writing | Philip Vallentin | Storyboard |
| Writing | Sharon Smith | Storyboard |
| Writing | Gabriele Zucchelli | Storyboard |
| Visual Effects | Trey Thomas | Animation Director |
| Writing | Padraig Collins | Storyboard |
| Visual Effects | Tim Allen | Animation |
| Production | Simon Quinn | Line Producer |
| Writing | Leonard Ripps | Original Story |
| Production | Derek Frey | Co-Producer |
| Visual Effects | Antony Elworthy | Lead Animator |
| Crew | Julie Hickson | Thanks |
| Crew | Barret Oliver | Thanks |
| Visual Effects | Jonny Ffinch | Visual Effects Producer |
| Editing | Stephen Perkins | Associate Editor |
| Art | Tim Browning | Art Direction |
| Art | Alexandra Walker | Art Direction |
| Sound | Tom Johnson | Sound Re-Recording Mixer |
| Visual Effects | Tim Ledbury | Visual Effects Supervisor |
| Production | Andrew Bonner | Production Coordinator |
| Sound | Rachael Tate | Assistant Sound Editor |
| Sound | David Slonaker | Orchestrator |
| Directing | Kev Harwood | First Assistant Director |
| Visual Effects | Tobias Fouracre | Lead Animator |
| Lighting | Toby Farrar | Gaffer |
| Directing | Richard Lake | Second Assistant Director |
| Crew | Lucy Benson | Visual Effects Editor |
| Crew | Jessie Thiele | Post Production Supervisor |
| Art | Dean Wares | Title Designer |
| Production | Alice Lister | Production Coordinator |
| Production | Faye Robinson | Production Coordinator |
| Sound | Steve Browell | Sound Effects Editor |
| Sound | Michael Higham | Music Editor |
| Sound | Bjørn Ole Schroeder | Supervising Dialogue Editor |
| Sound | Edgardo Simone | Orchestrator |
| Crew | Daniel Stern | Thanks |
| Crew | Thomas L. Wilhite | Thanks |
| Editing | Tom Kemplen | First Assistant Editor |
| Sound | Oliver Tarney | Supervising Sound Editor |
| Sound | Michael Semanick | Sound Re-Recording Mixer |
| Visual Effects | Brian Leif Hansen | Lead Animator |
| Sound | Michael Fentum | Sound Effects Designer |
| Crew | შელი დიუვალი | Thanks |
| Production | Caitlin Well | Casting Associate |
| Sound | Dillon Bennett | Sound Effects Editor |
| Art | Richard Morrison | Title Designer |
| Production | Joan Schneider | Unit Production Manager |
| Production | Jeffrey Broom | Production Accountant |
| Sound | Christopher Boyes | Sound Re-Recording Mixer |
| Production | Connie Nartonis Thompson | Associate Producer |
| Visual Effects | Dobrin Yanev | Lead Animator |
| Production | Jen Rudin | Local Casting |
| Art | Rick Heinrichs | Production Design |
| Sound | Jack Stew | Foley Artist |
| Writing | Jørgen Klubien | Story Developer |
| Writing | მერი შელი | Original Story |
| Visual Effects | Richard Baker | Stereoscopic Supervisor |
