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Harry Connick Jr. as Dr. Dennis Slamon |
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Tammy Blanchard as Nicole Wilson |
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Amanda Bynes as Jamie McGrath |
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Jennifer Coolidge as Tish |
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Angie Harmon as Lilly Tartikoff |
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John Benjamin Hickey as Blake Rogers |
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Regina King as Ellie Jackson |
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Swoosie Kurtz as Elizabeth |
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Paula Cale as Donna Slamon (as Paula Cale Lisbe) |
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Amy Madigan as Fran Visco |
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Bernadette Peters as Barbara Bradfield |
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Trudie Styler as Tina |
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Melissa McBride as Sally |
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J. Patrick McNamara as Dr. Rice |
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Jackson Hurst as Josh |
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Brandon Smith as Pharmacy Board Member |
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Bruce McKinnon as Dean Bradfield |
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Tom Nowicki as Carl Reinhardt |
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William Ragsdale as Andy Marks |
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Naima Lett as Nurse Carol (as Naima Imani Lett) |
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Griff Furst as Charlie Wilson |
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Maria Howell as Kate |
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Joe Nemmers as Ron Perelman |
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Rhoda Griffis as Bindy Blake |
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Lance E. Nichols as Dr. Brown |
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Louis Herthum as Dr. Banks |
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Kim Wall as Marci |
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Connor Hill as Sam Wilson Age 5 |
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Tyler Case as Sam Wilson Age 7 and 8 |
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Cooper Cason as Sam Wilson Age 14 |
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Sophia Watson as Joey Lyn Slamon Age 7 |
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Abby Rao as Joey Lyn Slamon Age 9 |
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Sam Richardson as Matt Slamon Age 3 - 5 |
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Ben Lux as Matt Slamon Age 7 (as Benjamin Lux) |
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Austin Lux as Matt Slamon Age 9 |
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Elliott Grey as Board Member |
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Andrew Matthews as Darrin Bradfield |
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Evan Gamble as Peter Wilson |
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Shanna Forrestall as Runner |
| Directing | Dan Ireland | Director |
| Production | Craig Zadan | Producer |
| Production | Neil Meron | Producer |
| Writing | Robert Bazell | Book |
| Writing | Vivienne Radkoff | Teleplay |
| Production | Renée Zellweger | Executive Producer |
| Production | Vivienne Radkoff | Executive Producer |
| Camera | James Chressanthis | Director of Photography |
| Production | Susan Edelman | Casting |
| Editing | Margaret Goodspeed | Editor |
| Camera | Christopher Nash | Dolly Grip |
| Sound | Halli Cauthery | Original Music Composer |
