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Karthi as Varun |
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Aditi Rao Hydari as Dr. Leela |
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RJ Balaji as Dr. Illyaas Hussain |
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Rukmini Vijayakumar as Dr. Nidhi |
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KPAC Lalitha as Achamma |
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Shraddha Srinath as Girija Kapoor |
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Delhi Ganesh as Col. Mithran |
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Sivakumar Ananth as Girish Reddy |
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Vipin Sharma as Dr. Leela's Father |
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Mir Sarwar as Muzaffar Khan |
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Harish Raj as Madhusoodhanan Pillai |
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Dhyana Madan as Rohini |
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Supyarde Singh as VC's sister-in-Law |
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Bejoy Nambiar as Cameo as Bus Passenger |
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Anand Krishnamoorthi as Cameo as Bus Passenger |
| Directing | Richard Anthony | Assistant Director |
| Editing | Sreekar Prasad | Editor |
| Directing | Mani Ratnam | Director |
| Sound | A.R. Rahman | Original Music Composer |
| Camera | Ravi Varman | Director of Photography |
| Production | Mani Ratnam | Producer |
| Art | Sharmishta Roy | Production Design |
| Crew | Brinda | Choreographer |
| Camera | C H Balu | Still Photographer |
| Writing | Bejoy Nambiar | Creative Producer |
| Directing | P. S. Keerthana | Assistant Director |
| Sound | Durga Chiranjeevi | Sound Editor |
| Costume & Make-Up | Serina Tixeira | Makeup Artist |
| Sound | S. Sivakumar | Sound Mixer |
| Visual Effects | Sandeep Mane | Visual Effects Producer |
| Production | Shalini Shankar | Line Producer |
| Sound | Anand Krishnamoorthi | Sound Designer |
| Sound | P. C. Vishnu | Foley Editor |
| Sound | Arun S Mani | Foley Editor |
| Writing | Mani Ratnam | Story |
| Writing | Mani Ratnam | Dialogue |
| Writing | Mani Ratnam | Screenplay |
| Crew | Sham Kaushal | Stunt Coordinator |
| Sound | Jonita Gandhi | Playback Singer |
| Costume & Make-Up | Eka Lakhani | Costume Designer |
| Art | A. Amaran | Art Direction |
