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Bill Murray as Bob Wiley |
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Richard Dreyfuss as Dr. Leo Marvin |
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Julie Hagerty as Fay Marvin |
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Charlie Korsmo as Sigmund "Siggy" Marvin |
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Kathryn Erbe as Anna Marvin |
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Tom Aldredge as Mr. Guttman |
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Susan Willis as Mrs. Guttman |
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Roger Bowen as Phil |
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Fran Brill as Lily Marvin |
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Brian Reddy as Carswell Fensterwald, M.D. |
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Doris Belack as Dr. Catherine Tomsky |
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Melinda Mullins as Marie Grady |
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Marcella Lowery as Betty, Switchboard Operator |
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Margot Welch as Gwen, Switchboard Operator |
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Barbara Andres as Claire, Dr. Marvin's Secretary |
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Aida Turturro as Prostitute |
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Joan Lunden as TV Announcer |
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Dennis Scott as Motorcycle Cop |
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Richard Fancy as Minister |
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Cortez Nance Jr. as Lobby Doorman |
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Reg E. Cathey as Howie / Director |
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Tom Stechschulte as Lennie / Producer |
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Russell Bobbitt as TV Crew Member |
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Stuart Rudin as Crazy Man |
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Charles Thomas Baxter as Nursing Home Guard |
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Donald J. Lee Jr. as Nursing Home Attendant |
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Lori Tan Chinn as Bus Driver |
| Directing | Frank Oz | Director |
| Editing | Anne V. Coates | Editor |
| Writing | Tom Schulman | Screenplay |
| Camera | Michael Ballhaus | Director of Photography |
| Sound | Miles Goodman | Original Music Composer |
| Production | Laura Ziskin | Producer |
| Crew | James Kindelon | Stunts |
| Crew | Steve Hart | Stunts |
| Crew | Bobby Burns | Stunt Double |
| Crew | Ted Barba | Stunts |
| Crew | Dennis Scott | Stunt Coordinator |
| Costume & Make-Up | Bernie Pollack | Costume Design |
| Art | Anne Kuljian | Set Decoration |
| Art | Leslie Dilley | Production Design |
| Art | Jack Blackman | Art Direction |
| Production | Glenn Daniels | Casting |
| Crew | Michael Steve Jones | Stunts |
| Sound | John K. Carr | Sound Editor |
| Visual Effects | Richard O. Helmer | Special Effects Supervisor |
| Art | Michael R. Clark | Painter |
| Sound | Pieter Hubbard | Sound Editor |
| Costume & Make-Up | Emanuel Millar | Hairstylist |
| Art | Roger G. Fortune | Set Designer |
| Directing | James W. Skotchdopole | First Assistant Director |
| Sound | Ed White | Sound Mixer |
| Writing | Alvin Sargent | Story |
| Art | Donald G. Helderle | Construction Foreman |
| Art | Brett C. Smith | Set Dresser |
| Sound | David Grannis | Assistant Sound Editor |
| Camera | Florian Ballhaus | First Assistant Camera |
| Art | Douglas Fox | Property Master |
| Sound | Liz Carlin | Assistant Sound Editor |
| Sound | Mel Metcalfe | Sound Re-Recording Mixer |
| Sound | Scott Shadden | Assistant Sound Editor |
| Writing | Laura Ziskin | Story |
| Art | Russell Bobbitt | Property Master |
| Art | Ken Scaife | Construction Coordinator |
| Sound | Doc Kane | ADR Mixer |
| Sound | Kenneth C. Mantlo | Boom Operator |
| Production | David C. Anderson | Unit Production Manager |
| Sound | John Phillips | Sound Editor |
| Sound | Hal Sanders | Sound Editor |
| Camera | Stuart Abramson | Key Grip |
| Directing | Donald J. Lee Jr. | Second Assistant Director |
| Art | Wayne Shepherd | Leadman |
| Art | Frank B. Nieves | Construction Foreman |
| Sound | Bruce Bell | Foley Mixer |
| Sound | Devon Heffley Curry | ADR Editor |
| Production | Bernard Williams | Co-Producer |
| Sound | Bill Phillips | Supervising Sound Editor |
| Sound | David J. Hudson | Sound Re-Recording Mixer |
| Sound | Edward Steidele | Foley Artist |
| Costume & Make-Up | Matthew W. Mungle | Makeup Artist |
| Sound | Catherine Harper | Foley Artist |
| Sound | Terry Porter | Sound Re-Recording Mixer |
| Camera | Arthur Blum | Dolly Grip |
| Directing | Susan Malerstein | Script Supervisor |
| Production | Tandi Slater | Production Accountant |
| Production | Dana Williams | Production Coordinator |
| Camera | David M. Dunlap | Camera Operator |
| Crew | Rafe Blasi | Unit Publicist |
| Lighting | Robert W. Meyers | Rigging Gaffer |
| Editing | James D.R. Hickox | Assistant Editor |
| Camera | Craig Kohtala | Best Boy Grip |
| Camera | Bobby Mancuso | Second Assistant Camera |
| Production | Lisa Lynn Kearsley | Production Coordinator |
| Lighting | James R. Tynes | Chief Lighting Technician |
| Sound | Nancy Fogarty | Music Editor |
| Camera | Barry Wetcher | Still Photographer |
| Editing | Christopher Cibelli | Assistant Editor |
| Costume & Make-Up | Hugo Peña | Costume Supervisor |
| Production | Sandy Isaac | Post Production Coordinator |
| Production | Charles Thomas Baxter | Location Manager |
